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LRRC3B is a gene frequently epigenetically inactivated in several epithelial malignancies and inhibits cell growth and replication. Data suggest that the LRRC3B gene could be involved in the process of carcinogenesis as a tumor suppressor gene.[5]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000179796 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000045201 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Haraldson K, Kashuba VI, Dmitriev AA, Senchenko VN, Kudryavtseva AV, Pavlova TV, Braga EA, Pronina IV, Kondratov AG, Rynditch AV, Lerman MI, Zabarovsky ER (2012). "LRRC3B is a gene frequently epigenetically inactivated in several epithelial malignancies and inhibits cell growth and replication". Biochimie. 94 (9): 1151–1157. doi:10.1016/j.biochi.2012.01.019. PMID 22321817.